Detalji o radu
Broj pregleda rada: 18
Naslov: Superficial CD34-positive Fibroblastic Breast Tumor: A Case Report
DOI: 10.14744/etd.2021.53386
Godina: 2022
Autori: VEDRAN DRAGIŠIĆ, JOSIP MIŠKOVIĆ, VJEKOSLAV ČULJAK, JOŠKO PETRIČEVIĆ, NIKICA ŠUTALO
Sažetak: Background: CD34 is a transmembrane phosphoglycoprotein that plays a role in modulating cell adhesion and myofibroblastic differentiation. A superficial CD34-positive fibroblastic tumor was first identified as a clinical and pathological entity in
2014; it is a rare mesenchymal neoplasm of borderline malignancy that can occur in the superficial adipose tissue anywhere
on the body.
Case Report: This is a case of a female patient aged 38 years who was referred to a surgeon due to tumefaction in the left
paraxial region. The tumor was excised in toto and pathohistological analysis confirmed a superficial CD34-positive fibroblastic tumor. Immunohistochemical staining was positive for CD34 and additional analysis for signal transducer and activator of
transcription and mouse double minute 2 proteins revealed negative staining. It was decided that no additional therapy was
needed; however, regular follow-ups were recommended.
Conclusion: This case posed an additional diagnostic and therapeutic challenge due to the localization of the tumor in the
breast of a female patient. Special care was needed to exclude a possible breast neoplasm as well as dermal or soft tissue
neoplasm. Diagnosis of a superficial CD34-positive fibroblastic tumor should be considered in all CD34-positive tumors with
bizarre, irregular nuclei and no proliferative activity
Vrsta rada: Studija slučaja
Izdanje: Erciyes medical journal
Znanstvena područja:
BIOMEDICINA I ZDRAVSTVO